ABSTRACT
Objective To discuss the imaging findings of the sex cord-stromal tumors of ovary.Methods The pathologically confirmed CT and MRI images of 69 patients with sex cord-stromal tumors of ovary were collected retrospectively.Results Among 69 cases of ovarian sex cord-stromal tumors,there were fibrothecoma 3 1 cases,thecal cell tumor 1 9 cases,fibroma 1 2 cases,granulosa cell tumors 5 cases and stromal sarcomas 2 cases.CT and MRI had detected all the 69 tumors.Most of the tumors (52 cases,accounting for 75%)were presented as mainly solid tumors combined with cystic changes,some (13 cases,accounting for 19%)were presented as all solid and a few cases (4 cases,accounting for 6%)were presented as cystic tumors.The tumors were round or oval,with clear boundary,which showed low density,and either no obvious enhancement or mild delayed enhancement on CT scan.The solid part of tumors showed low signal on T2WI and slightly higher signal on diffusion weighted imaging(DWI).Conclusion The sex cord-stromal tumors of ovary are mainly solid tumors combined with cystic changes,with clear boundary,either with no obvious enhancement or mild delayed enhancement and low signal on T2WI and slightly higher signal on DWI.The study shows that the above imaging features are helpful to improve the diagnostic accuracy of sex cord-stromal tumors of ovary.
ABSTRACT
Objective To investigate the metabolites of serum samples from liver cirrhotic patients with or without minimal hepatic encephalopathy,and even overt hepatic encephalopathy,then to find out diagnostic markers for minimal hepatic encephalopathy.Methods High performance liquid chromatography-orbit trap mass spectrometry (UPLC/LTQ-Orbit trap MS) technology was applied to analyze the serum metabolites from 38 patients of liver cirrhosiswith hepatitis B and 33 healthy volunteers.Results The serum metabolites of patients with simple liver cirrhosis were different from those of patients with minimal or overt hepatic encephalopathy.The serum metabolites of patients with minimal hepatic encephalopathy was mostly similar with those of overt hepatic encephalopathy patients.Arginase,L-tyrosine,glutamic acid,two L-phenylalanine peptide,homovanillic acid,omithine,L-serine were increased in patients with minimal or overt hepatic encephalopathy,and hypoxanthine decreased in patients with minimal or overt hepatic encephalopathy patients.Conclusions The serum metabolites of patients with minimal hepatic encephalopathy are mostly similar to those of patients with overt hepatic encephalopathy.Arginase,L-tyrosine,glutamic acid,two L-phenylalanine peptide,homovanillic acid,ornithine,L-serine maybe the early metabolites biomarkers to diagnose minimal hepatic encephalopathy.Hypoxanthine is likely to be an effective complement to treat patients with hepatic encephalopathy.